A paradigm for development and evolution of adult patterns. Lundi 10 décembreà 11h00 Centre de Recherche — Paris Amphithéâtre Constant-Burg — 12 rue Lhomond, Paris 5e How fish colour their skin: A paradigm for development and evolution of adult patterns Colour patterns are prominent features of most animals; they are highly variable and evolve rapidly leading to large diversities between species even within a single genus.
As targets for natural as well as sexual selection, they are of high evolutionary significance. The zebrafish Danio rerio displays a conspicuous pattern of alternating blue and golden stripes on the body and on the anal- and tailfins.
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Pigment cells in zebrafish — melanophores, iridophores and xanthophores — originate from neural crest-derived stem cells associated with the dorsal root ganglia of the peripheral nervous system. Clonal analysis indicates that these progenitors remain multipotent and plastic beyond embryogenesis well into metamorphosis, when the adult colour pattern develops. Pigment cells share a lineage with neuronal cells of the peripheral nervous system; progenitors spread along the spinal nerves. The proliferation of pigment cells is regulated by competitive interactions among cells of the same type.
Palais des Congrès, Liège Belgium.
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June 04 — 05, Steigenberger Grandhotel Petersberg. Königswinter near Bonn. Hollywood, California, November Institut Curie Paris. Transport and transfert of melanosomes : From the coat color to melanoma. Fez, Maroc. Lausanne, Suisse. CSK, a new player in melanomagenesis? Modèles murins de mélanomes. Invité 3rd International Melanoma Workshop Invité 16th Meeting of the European society for Pigment cell research Wellcome Trust conference Center, Hinxton Royaume-uni Septembre Biological and mathematical modeling of melanocyte development.
Invité 6èmes journées scientifiques, Ecole de Cancérologie Roscoff le 28 avril Mécanismes moléculaires et cellulaires impliqués dans le mélanomes. Invité 15th PASPCR, Memphis USA Septembre Replacement of a large minority of smooth muscle cells by melanocytes during development in the ductus arteriosus does not allow its closure and leads to postnatal death.
Cité Internationale universitaire.